SPOT-ONFlea & Tick

K9 Advantix Review

83/100

Topical flea and tick treatment that also repels mosquitoes, biting flies, and lice — the only topical with mosquito repellent action. Important for dogs in heartworm-endemic areas.

$47.99 at BestVetCare
Active Ingredient
Imidacloprid + Permethrin + Pyriproxyfen
Duration
30 days
Minimum Age
7 weeks+
Retail Price
$59.99 (4-pack)

Pros

  • Repels mosquitoes (unique among topicals)
  • Kills AND repels fleas and ticks
  • Also kills chewing lice
  • Waterproof after 24 hours

Cons

  • TOXIC to cats — do not use in cat homes
  • Strong chemical odor at application
  • Greasy residue
  • Not a heartworm preventive

Who It's Best For

Dogs in mosquito-heavy areas. Outdoor working dogs. Homes without cats. Heartworm-endemic regions.

Alternatives

Not the right fit? Here are other Flea & Tick treatments worth considering:

Frontline Plus Seresto Advantage Multi